Patching up the heart

Patching up the myocardium.

Cell therapy, while retaining promise for cardiac regeneration, has thus far been encumbered by variable and unpredictable fates of delivered cells. In a recent issue of PNAS, Godier-Furnémont and colleagues describe a new strategy to regulate cell delivery by promoting specific migration and growth factor secretion behaviors of implanted cells from a decellularized matrix via biochemical preco...

Patching Up X-trees

A fundamental problem in many areas of classification, and particularly in biology, is the reconstruction of a leaf-labeled tree from just a subset of its induced subtrees. Without loss of generality, we may assume that these induced subtrees all have precisely four leaves. Of particular interest is the question of determining whether a collection of quartet subtrees uniquely defines a parent t...

Enhancing Patching Performance Through Double Patching

Patching is an efficient bandwidth-sharing technique for video-on-demand systems. Its performance, however, has limitation: as the time distance to the last regular multicast enlarges, the patching cost for new requests increases and eventually, a new regular multicast must be scheduled to balance the cost. In this paper, we address this problem by proposing a new technique called Double Patchi...

Prohibiting AIDS testing in the health insurance context: patching up a patchwork system.

Prevalence of Heart Failure in the Cases of Beta-thalassemia Major; Two Years Follow-Up

  Inroduction: Heart failure (HF) is an important cause of morbidity and mortality in the cases of Beta-thalassemia major. The purpose of this study was to estimate HF prevalence in these patients and to assess the survivability of those who were treated with intensive chelating therapy.   Design and methods: This cross sectional study included 72 beta-thalassemia major cases, the mean age at t...